Drug Interactions With Meridia
Drug interactions can occur when certain other medications are taken with Meridia, and some of these interactions can affect the levels of medicines in your blood, thus increasing your risk of side effects. Other interactions can cause a group of symptoms, such as serotonin syndrome, which is very dangerous. Talk with your healthcare provider about the possible drug interactions that may apply specifically to you, before you start taking Meridia.
Some medicines may interact with Meridia (sibutramine hydrochloride monohydrate), and following, is a list of these medicines:
* Certain antifungal or antibiotics medications
* Certain pain medications, including:
o Meperidine or Demerol
o Tramadol or Ultracet, Ultram
o Fentanyl or Duragesic, Fentora, Actiq, Sublimaze
o Pentazocine or Talwin
* Cold, cough, or allergy medicines
* Ergot medications, such as the following:
o Methylergonovine or Methergine
o Pergolide or Permax
o Bromocriptine or parlodel
o Ergotamine or Bellamine S, Ergomar, Cafergot
o Dihydroergotamine or Migranal
o Ergonovine
* Lithium or Lithobid, Eskalith
* Monoamine oxidase inhibitors or MAOIs, including the following medicines:
o Rasagiline or Azilect
o Tranylcypromine or Parnate
o Isocarboxazid or Marplan
o Selegiline or Eldepryl, Zelapar, Emsam
o Phenelzine or Nardil
* Other weight-loss medications
* SNRI or SSRI medications, such as those listed below:
o Escitalopram or Lexapro
o Paraxetine or Paxil, Pexava, Paxil CR
o Citalopram or Celexa
o Milnacipran or Savella
o Desvenlafaxine or Pristiq
o Fluvvoxamine or Luvox, Luvox CR
o Duloxetine or Cymbalta
o Fluoxetine or Prozac, Selfemra, Sarafem
o Venlafaxine or Effexor XR, Effexor
o Sertraline or Zoloft
* St. John’s wort
* Tricyclic antidepressants, which include the following:
o Desipramine or Norpramin
o Nortriptyline or Pamelor
o Clomipramine or Anafranil
o Maprotiline or Ludiomil
o Amitriptyline or Elavil
o Imipramine or Tofranil
o Amoxapine or Asendin
o Doxepin or Sinequan
o Trimipramine or Surmontil
o Protriptyline or Vivactil
* Triptans, which includes the following:
o Frovatriptan or Frova
o Zolmitriptan or Zomig
o Rizatriptan or Maxalt
o Almotriptan or Axert
o Sumatriptan or Imitrex or sumatriptan/naproxen sodium or Treximet
o Eletriptan or Relpax
o Naratriptan or Amerge
* Tryptophan
Below, is a detailed explanation of potentially negative interactions that can occur, when Meridia is combined with any of the drugs listed above.
If you are taking Meridia and it is combined with any antifungal or antibiotic medications, these can increase the level of Meridia in your blood, which will increase your risk of Meridia side effects. Before mixing Meridia with any antibiotic or antifungal medicine, talk with your healthcare provider.
Pain Medications
A group of symptoms called serotonin syndrome can develop when Meridia is combined with certain pain medications. These symptoms include hallucinations, fast heartbeat, confusion, feeling faint, sweating, fever, difficulty walking, diarrhea, and muscle spasms. If you have any of these symptoms, call your healthcare immediately, as serotonin syndrome can be extremely dangerous. Before taking these medications together with Meridia, talk with your healthcare provider.
Before combining Meridia with any cold, cough, or allergy medicines, including non-prescription medicines, seek the advise of your healthcare provider. Many of these products contain medications that can cause dangerous interactions with Meridia.
Serotonin syndrome can develop if you take Meridia with ergot medications. Talk with your healthcare provider before taking any of these medications together. If you have any symptoms of serotonin syndrome, call your healthcare provider immediately, as it can be extremely dangerous.
If you are taking Meridia and it is combined with lithium this can cause a group of symptoms referred to as serotonin syndrome. Before taking any of these medications together, talk with your healthcare provider, and if you have any symptoms of serotonin syndrome, call your healthcare provider right away, as this symptom can be very dangerous.
You can suffer life-threatening side effects if you are taking Meridia and it is combined with MAOI or Monoamine Oxidase Inhibitors. It is strongly advised that you do not take Meridia with MAOI at the same time nor even within two weeks of each other.
Before taking Meridia with any other weight-loss medications, consult with your healthcare provider. Other weight-loss medications that also affect certain brain chemicals should not be taken or combined with Meridia.
Serotonin syndrome can develop if you are taking Meridia and it is combined with SNRIs or SSRIs. Talk with your healthcare provider before you take these medications together. If you experience any symptoms of serotonin syndrome, contact your healthcare provider immediately, since this is a very dangerous symptom.
If you are taking St. John’s wort and it is combined with Meridia, this can cause a group of symptoms called serotonin syndrome. Your healthcare provider can advise you concerning the interaction of these medications, before you begin taking Meridia. If you should develop any symptoms of serotonin syndrome, which can be extremely dangerous, call your healthcare provider immediately.
The level of tricyclic antidepressants in your blood will increase if you are taking Meridia with tricyclic antidepressants. If this occurs, your healthcare provider may need to reduce your dosage of tricyclic antidepressant.
A group of symptoms called serotonin syndrome can develop if you are taking Meridia with a triptan migraine medication. Before you start taking these medications together, talk with your healthcare provider. Because of the extreme dangers of serotonin syndrome, you should call your healthcare provider immediately if you start to experience these syndromes.
If you are taking Meridia and it is combined with tryptophan, this drug interaction can cause a group of symptoms called serotonin syndrome. Before taking these medications together, you need to talk with your healthcare provider, and if you should experience symptoms of serotonin syndrome due to its dangerous effects, seek the medical attention of your healthcare provider immediately.
There is a possibility that some other drugs that may interact with Meridia may not have been discussed in this article. As a result, you must talk with your healthcare provider or your pharmacist about possible drug interactions with Meridia that may apply to you directly.
18 Positive Reviews
1 Negative Review 
